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- Bettter oral bioavailability than acyclovir

- MORE effective against VZV than acyclovir

- inhibitor of Influenza A and B neuraminidases

- causing conformational change within the enzyme's active site

- Rapid absorption and activation by esterases in GI and liver

- cleared by kidney

- prophyulaxis

- early treatment

- MOA same as oseltamivir

- NO resistance has been found in healthy people

- inhibit RNA and DNA viruses

- inhibit mRNA synthesis

- increased bilirubin, anemia, and rigor (systemic)

- wheezing and rash (aerosolized)

- HBsAG

- Anti - HBs

- Anti-HBc

- HBeAG

- hepatitis B surface antigen

- ONLY way to diagnose active HBV

- Hepatitis B surface antibody

- Protection against HBV secondary to vaccination or preious exposure

- hepatitis B core antibody

- represents ongoing infection

- hepatitis e antigen

- represents active viral repplication

Lamivudine

Adfovir

Telvivudine

Tenofivir

Entecavir

LATTE!!!!

*** inhibits reverse transcriptase, incorporates into viral DNA

recombinant DNA => stimulating body's immune system

- anti-hepatitis for type B and C

- dose adjustment in renal insufficiency