1.6 asse Drugs
Pharmaceutical Sciences 1.6 with Chakraborty at Roseman University of Health Sciences
About this deck
By: jacob mantz
Created: 2011-11-16
Size: 58 flashcards
Views: 49
Created: 2011-11-16
Size: 58 flashcards
Views: 49
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Albuterol Proventil®
β2 Agonists Short- acting
Albuterol tabs VoSpire®
β2 Agonists Short- acting
Levalbuterol Xopenex®
β2 Agonists Short- acting
Metoproterenol Alupent®
β2 Agonists Short- acting
Pirbuterol Maxair®
β2 Agonists Short- acting
Arformoterol Brovana®
β2 Agonists Long- acting
Formoterol Foradil®
β2 Agonists Long- acting
Salmeterol Serevent®
β2 Agonists Long- acting
Terbutaline Brethine®
Selective β2 agonist
Dopamine Inotropin
D1 , D2 receptor agonist
Fenoldopam Corlopam
D1 receptor agonist
Bromocriptine Parlodel
D2 Receptor agonist
Epinephrine (EPI) Adrenalin
Nonselective α and β agonist
Norepinephrine (NE) Levophed
Nonselective α and β agonist
Amphetamine (Dexedrine)
NE + DA Releaser
Lisdexamfetamine (Vyvanse)
NE + DA Releaser
Methylphenidate (Ritalin)
NE + DA Uptake1 inhibitor - special capsul
Atomoxetine (Strattera)
NE + DA Uptake1 inhibitor - liver toxicity
Modafinil (Provigil)
Unknown MOA (Indirect Acting Sympathomimetic) for Narcolepsy
Armodafinil (Nuvigil)
Unknown MOA (Indirect Acting Sympathomimetic) for Narcolepsy
Amphetamines do what?
release NE and DA plus inhibit NE and DA uptake1 - Treat ADHD, Narcolepsy and are Indirect acting sympathomimetics
Methylphenidates do what?
inhibit NE and DA uptake1 - treat ADHD, Narcolepsy and are Indirect acting sympathomimetics
Guanfacine (Intuniv)
agonists of CNS postsynaptic α2A receptors → improve firing rate of prefrontal cortex nerves (treat ADHD)
Clonidine (Kapvay)
agonists of CNS postsynaptic α2A receptors → improve firing rate of prefrontal cortex nerves (treat ADHD)
Phenylzine (Nardil®)
MAO-A&B Inhibitor - Depression (2nd line Rx)
Tranylcypromine (Parnate®)
MAO-A&B Inhibitor - Depression (2nd line Rx)
Selegiline (Eldepryl®)
(MAO-B selective) - Parkinson’s disease
Rasagiline (Azilect®)
(MAO-B selective) - Parkinson’s disease
Tramadol Ultram
MAOI - Analgesic
Propoxyphene Darvon
MAOI - Analgesic
Methadone Dolophine
MAOI - Analgesic
Meperidine Demerol
MAOI - Analgesic
Humalog
Insulin lispro - Rapid
Humulin (R )
Regular - Short
Humulin (N)
NPH - Intermediate
Lantus
Insulin glargine - Long
Insulin Secretogogues
(Sulfonylureas & Meglitinides "glinides") cause the pancreas to secrete more insulin | Hypoglycemia (ADR)
Glyburide
a sulfonylurea
Glyipizide
a sulfonylurea
Glimepiride
a sulfonylurea
Repaglinide (Prandin)
a Meglitinide
Nateglinide (Starlix)
a Meglitinide
Euglycemic Agents
(biguanides & thiazolidinediones) do not stimulate insulin release and thus, do not usually cause hypoglycemia like the insulin secretogogues
Biguanides—Mech and ADR
increases insulin sensitivity & blocks hepatic uptake of lactic acid (ADR)
Metformin
a biguanide (the major one)
Hypoxic
Low amounts of oxygen
Thiazolidinediones
like biguanides in that it improves insulin sensitivity, decreases gluconeogenisis and may cause lactic acidosis. But also hepatictoxcity & Cardiotoxicity
Rosiglitazone (avandia)
a thiazolidinedione
Pioglitazone (actos)
a thiazolidinedione
α-Glucosidase Inhibitors—Mechanism of Action
competitive inhibitors, mediate blood glucose
Miglitol (glyset)
an α-Glucosidase Inhibitor
Acarbose (Precose)
an α-Glucosidase Inhibitor
Incretin System
anticipatory hormon for insulin sucretion ( Glucagon-like peptide-1 (GLP-1) & Glucose-dependent insulinotropic peptide (GIP) )
Exenatide (Byetta)
an Exogenous Incretin - a long-acting agonist of the glucagon-like peptide 1 (GLP-1) receptor
Liraglutide (Victoza)
an Exogenous Incretin - a long acting agonist of GLP-1
DPP-4
Dipeptidyl peptidase-4 (DPP-4) is the enzyme which breaks down incretin proteins - DPP-4 inhibitors lead to longer affect of incretins
sitagliptin
a DDP-4 inhibitor
pramlintide (Symlin)
a synthetic version of amylin
About this deck
By: jacob mantz
Created: 2011-11-16
Size: 58 flashcards
Views: 49
Created: 2011-11-16
Size: 58 flashcards
Views: 49
About StudyBlue
STUDYBLUE makes things that make you better at school.
Things like online flashcards with photos and audio.
Things like personalized quizzes and friendly reminders about when (and what) to study next.
Think of it as a digital backpack™: access to all of your study materials online and on your phone.
STUDYBLUE exists to make studying efficient and effective for every student, for free. Join us.
“I have used this website for three exams, and I see a huge difference in my test results.”
Naj
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