Blood 2

Anatomy & Physiology 2265 with Kimball at University of Connecticut

About this deck

By: Rachel Likar
Textbook:

A Photographic Atlas for the Anatomy and Physiology Laboratory Seventh Edition

Human Anatomy
Human Anatomy AND Physiology: A Functional Approach
Created: 2012-02-14
Size: 29 flashcards
Views: 11

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Neutrophils have what immune response?

Inflammation, phagocytosis

Basophils have what immune response?

Secrete histimine (vasodilator) and heparin (anticoagulant)

Eosinophils have what immune response?

Defend against parasitic worms, anti-inflammatory

Monocytes have what immune response?

Enter tissue and differentiate into macrophages

Lymphocytes have what immune response?

B cells - humoral immunity
T cells - cell-mediated immunity

Platelets are regulated by...?

Thrombopoietin

What are the major lymphatic vessels?

Right lymphatic duct and thoracic duct

What are the primary lymphoid tissues/organs?

Bone marrow and thymus

What are the secondary lymphoid tissue/organs?

Lymph nodes, spleen, Peyer's Patches, tonsils

2 functions of lymphatic system?

body fluid homeostasis
immune system

Which lymphocytes initiate their development in bone marrow and migrate to thymus to mature?

T CELLS

Which lymphocytes mature in the bone marrow?

B CELLS

Which lymphocyte responds to multiple antigens and acts as immune "surveillance"?

NK (natural killer) cells

Which lymphocytes give rise to antibody-secreting plasma cells?

B cells

What t cell directly kills foreign cells, but must be activated first?

cytotoxic t cells

what t cell initiates and oversees immune response?

helper t cells

which t cell turns off the immune response once it has been activated?

suppressor t cell

What are the receptors on cytotoxic t cells? on helper t cells? on supressor cells?

CD8 - cytotoxic
CD4 - helper t cells
CD25 - suppressor cells

Definition of an antigen?

Any foreign molecule that can trigger specific immune response (production of antibodies)

Definition of an antibody?

Defense protein secreted by specific B lymphocytes
"Y" shape
variable regions bind antigen
constant region involved in effector mechanism

What is the roles of MHC proteins?

to identify "self" from "non-self"

MHC class 1

on all nucleated cells
recognized by cytotoxic t cells

MHC class 2

on macrophages, B cells, and dendritic cells, recognized by helper T cells

Plasma cells are derived from ? What do they produce?

Derived from activated B cells
antibody factories

Where do macrophages come from? What do they do?

They are derived from monocyte lineage
they phagocytize the antigen

Where are mast cells from? What do they do?

Derived from bone marrow
release histamine, important for vasodilation/ inflammation

What is the antigen for blood types A, B, AB, and O? The antibodies?

A = antigen A, anti-B
B = antigen B, anti-A
AB = antigen AB, none
O = no antigen, anti-A and anti-B

Blood types Rh+ and Rh- have what antigen/antibody?

Rh + = antigen Rh, none
Rh - = none, anti-Rh

What is RHOGAM?

it is a drug given to a pregnant woman just before going into labor. If a mother is Rh - and the baby is Rh + then the mother would produce antibodies if exposed to the fetal blood. This drug prevents the mother from creating antibodies.