Ch.6: Binary Fission & Peptidoglycan Cell Wall Synthesis
Biology 351 with Wing at University of Nevada-Las Vegas
About this deck
By: Ally Gesmundo
Textbook:
Brock Biology of Microorganisms (12th Edition)
Created: 2011-03-01
Size: 12 flashcards
Views: 20
Textbook:
Brock Biology of Microorganisms (12th Edition)Created: 2011-03-01
Size: 12 flashcards
Views: 20
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Binary Fission
refer to as GROWTH rather than reproduction
-this is how bacterial cells grow/divide
-chromosomes duplicate, go to diff sides of cell
-elongate
-divide
-this is how bacterial cells grow/divide
-chromosomes duplicate, go to diff sides of cell
-elongate
-divide
Divisomes
-site of Fts and min proteins
FtsZ / FtsZ ring
-key Fts protein in cell division
-forms a contractile ring that pinches off
-related to tubulin
-forms a contractile ring that pinches off
-related to tubulin
min proteins
-help identify location of midpoint in cell where the cell will divide (minCD)
Mutant cells lacking minCD gene
divide unevenly to generate one large cell and one mini-cell
MreB protein
-necessary for rod shape
-forms polymers
-similar to actin
-forms polymers
-similar to actin
Bactoprenol
-lipid carrier molecule
-acts as the peptidoglycan precursor CONVEYOR
-transport the NAM/NAG/pentapeptide peptidoglycan precursor across the cytoplasmic membrane to the site of cell wall synthesis
-acts as the peptidoglycan precursor CONVEYOR
-transport the NAM/NAG/pentapeptide peptidoglycan precursor across the cytoplasmic membrane to the site of cell wall synthesis
Transpeptidation Reaction
-FINAL step of peptidoglycan cell wall synthesis
-cross-links layers of peptidoglycan to each other
-cross-links layers of peptidoglycan to each other
Peptidoglycan Cell Wall Synthesis OVERVIEW
1. Bactoprenol activity (starts at FtsZ ring)
2. Transpeptidation reaction
2. Transpeptidation reaction
1. Bactoprenol activity
- Bactoprenol transports NAM/NAG/pentapeptide peptidoglycan precursors to the site of cell wall synthesis.
- AUTOLYSINS create small openings in the PRE-EXISTING cell wall.
- NEW cell wall material is then ADDED across these openings.
- AUTOLYSINS create small openings in the PRE-EXISTING cell wall.
- NEW cell wall material is then ADDED across these openings.
2. Transpeptidation reaction
-cross-links the layers of peptidoglycan to each other.
Why must the introduction of NEW cell wall precursors into the EXISTING wall be TIGHTLY coordinated?
if not coordinated tightly and properly, AUTOLYSIS (spontaneous cell lysis) can occur!!
About this deck
By: Ally Gesmundo
Textbook: Brock Biology of Microorganisms (12th Edition)
Created: 2011-03-01
Size: 12 flashcards
Views: 20
Textbook:
Brock Biology of Microorganisms (12th Edition)Created: 2011-03-01
Size: 12 flashcards
Views: 20
About StudyBlue
STUDYBLUE makes things that make you better at school.
Things like online flashcards with photos and audio.
Things like personalized quizzes and friendly reminders about when (and what) to study next.
Think of it as a digital backpack™: access to all of your study materials online and on your phone.
STUDYBLUE exists to make studying efficient and effective for every student, for free. Join us.
“I have been getting MUCH better grades on all my tests for school. Flash cards, notes, and quizzes are great on here. Thanks!”
Kathy
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