CNS Drugs 2
Pharmacology 521 with Oakes at University of Wisconsin - Madison
About this deck
By: Dan Ruhland
Created: 2011-11-07
Size: 51 flashcards
Views: 25
Created: 2011-11-07
Size: 51 flashcards
Views: 25
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Albuterol MoA
Beta 2 Agonist
Albuterol Use
Asthma, COPD
Albuterol Adverse Effects
HA, tremor, HTN; Significantly fewer cardiac side effecs because of Beta selectivity
Amphetamine MoA
Catecholamine Storage Inhibitor
weakly inhibit MOA
block NET and DAT
weakly inhibit MOA
block NET and DAT
Amphetamine Use
ADHD, Narcolepsy
Amphetamine Adverse Effects
HTN, arrhythmia, seizure, psychotic disorder w/ prolonged use
Restlessness, dysphoric mood, rebound fatigue, addiction potential
Restlessness, dysphoric mood, rebound fatigue, addiction potential
Amphetamine Contraindications
CV disease, Glaucoma, Hyperthyroidism, MAOI therapy, HTN
Atenolol MoA
Beta 1 Antag
Atenolol Use
HTN, Angina, Heart failure
Atenolol Adverse Effects
Atrioventricular block, Bradyarrhythmia, less bronchospasm
Sedation, decreased libido, depression, dyspnea
Sedation, decreased libido, depression, dyspnea
Atenolol Contraindications
Asthma, COPD, shock
Atropine MoA
Muscarinic Antagonism, blocks all subtypes
Atropine Use
Anticholinesterase Overdose, acute bradycardia, anesthetic procedure
Atropine Adverse Effects
Cardiac arrhythmia, coma, respiratory depression, raised intraocular pressure
Tachycardia, constipation, xerostomia, blurred vision
Tachycardia, constipation, xerostomia, blurred vision
Atropine Contraindications
Narrow-angle glaucoma
Baclofen MoA
GABA-b receptor Agonist
Bromocriptine MoA
D-2 Agonist
Capsaicin MoA
Causes release of Substance P from sensory neurons
Clonidine MoA
Alpha-2 Adrenergic Agonist
Clonidine Use
HTN, Opioid withdrawal, Cancer pain
Clonidine Adverse Effects
Bradycardia, Heart Failure
Hypotension, constipation, xerostomia
Hypotension, constipation, xerostomia
Clonidine Contraindications
MAO-I therapy
Cocaine MoA
Catecholamine Reuptake Inhibitor (NET)
Cocaine Use
Mucosal and ophthalmic local anesthetic, Diagnosis of Horner's syndrome pupil
Cocaine Adverse Effects
Accelerates atherosclerosis, tachycardia, Cardiotoxicity, seizure
CNS depression/excitation, anxiety, Abuse
CNS depression/excitation, anxiety, Abuse
Naloxone Use
Opioid Antagonist
Nicotine MoA
Nn and Nm Agonist
Nicotine Use
Smoking cessation, insecticide
Nicotine Adverse Effects
Increase GI activity, N&V, diarrhea, Increased BP
High doses can cause seizure
High doses can cause seizure
Nicotine Interactions
Additive w/ CNS stimulants
Ondansetron MoA
5-HT3 Antagonist
Ondansetron Use
Prevent N&V caused by chemotherapy, radiation therapy, and surgery
Phenylephrine MoA
Alpha-1 Adrenergic Agonist
Phenylephrine Use
Ophthalmic Hyperemia, Nasal congestion, Hypotension, IV for shock
Phenylephrine Adverse Effects
Cardiac arrhythmia, HTN
HA, insomnia, nervousness, rebound nasal congestion
HA, insomnia, nervousness, rebound nasal congestion
Phenylephrine Contraindications
Narrow-angle glaucoma, HTN, tachycardia
Prazosin MoA
Alpha-1 Antagonist
Prazosin Use
HTN, BPH
Prazosin Adverse Effects
Pancreatitis, Hepatotox
Postural Hypotension w/ first dose (given at bedtime), dizziness, sedation
Postural Hypotension w/ first dose (given at bedtime), dizziness, sedation
Ranitidine MoA
Histamine-2 Antagonist
Ranitidine Use
Gastric ulcers, GERD
Reserpine MoA
Catecholamine Storage Inhibitor, Irreversibly inhibits VMAT
Reserpine Use
HTN
Reserpine Adverse Effects
Cardiac arrhythmia, GI hemorrage, thrombocytopenia, impotence, psychotic depression
Dizziness, nasal congestion
Dizziness, nasal congestion
Reserpine Contraindications
GI disease, depression, electroshock therapy, renal failure
Strychnine MoA
Glycine receptor blockage
Strychnine Use
Pesticide which causes convulsant action
Yohimbine MoA
Alpha-2 Antagonist
Increased NE release
Increased NE release
Yohimbine Use
Impotence
Yohimbine Adverse Effects
Bronchospasm, nervousness, tremor, anxiety, agitation, increased BP, antidiuresis
Yohimbine Contraindications
inflammation of sex organs or prostate, use of mood altering drugs, Gastric/duodenal ulcers, pregnancy, psychiatric patient, renal or liver disease
About this deck
By: Dan Ruhland
Created: 2011-11-07
Size: 51 flashcards
Views: 25
Created: 2011-11-07
Size: 51 flashcards
Views: 25
About StudyBlue
STUDYBLUE makes things that make you better at school.
Things like online flashcards with photos and audio.
Things like personalized quizzes and friendly reminders about when (and what) to study next.
Think of it as a digital backpack™: access to all of your study materials online and on your phone.
STUDYBLUE exists to make studying efficient and effective for every student, for free. Join us.
“Simply amazing. The flash cards are smooth, there are many different types of studying tools, and there is a great search engine. I praise you on the awesomeness.”
Dennis
Dennis