Chemical ( fixative solution)
Physical ( heat and dessication)
Help maintain the proper relationship between cell and extracellular substances such connective tissue fibers and amorphous ground substances.
Bring out refractive index
render cell constituents insolunle
Choice of Fixative
What fixative demostrate chromaffin granules?
What special stain use bounin a mordate?
What are the preferred fixative for nucleic acids?