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- Wisconsin
- University of Wisconsin - LaCrosse
- Biology
- Biology 413
- Volk
- Mycotoxicosis/Mycetismus
Mycotoxicosis/Mycetismus
Biology 413 with Volk at University of Wisconsin - LaCrosse
About this deck
By: Katie Josephson
Created: 2012-03-25
Size: 23 flashcards
Views: 11
Created: 2012-03-25
Size: 23 flashcards
Views: 11
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Secondary Metabolites
Produced from intermediates in normal metabolism by specific enzymatic pathways
Produced when other cell requirements have been met
Used in competition for resources
Produced when other cell requirements have been met
Used in competition for resources
Diseases of plants caused by Fusarium sp.
Ear rot of corn
Head scab of grains
Head scab of grains
Vomitoxin
Produced by Fusarium sp. (graminearum)
DON is a trichothecene - acts as a nucleation site for bubble formation - causes beer to spurt out when opened
Virulence factor in ear rot
DON is a trichothecene - acts as a nucleation site for bubble formation - causes beer to spurt out when opened
Virulence factor in ear rot
Zearalenone
Produced by Fusarium sp.
An estrogen analog that causes reproductive problems in livestock
Ralgro - commercial formulation used as anabolic steroid (inc. weight gain and suppressed menstruation)
An estrogen analog that causes reproductive problems in livestock
Ralgro - commercial formulation used as anabolic steroid (inc. weight gain and suppressed menstruation)
Tricothecenes
Protein synthesis inhibitors
Bind directly to ribosomes
Cause of Alimentary Toxic Aleukia
Thought to be involved in Yellow Rain
Bind directly to ribosomes
Cause of Alimentary Toxic Aleukia
Thought to be involved in Yellow Rain
Tricothecenes and ATA
ATA is caused by T-2 toxin
Produced by F. poae, F. sporotrichioides and F. tricinctum
Optimal production during freezing/thawing cycles
Produced by F. poae, F. sporotrichioides and F. tricinctum
Optimal production during freezing/thawing cycles
Satratoxins
Another kind of tricothecene - chemical form that involves a fused ring = macrocyclic tricothecenes
Made by Stachybotrys - causes sick building syndromes - buildings with structural or mechanical defects - inc. moisture accumulation - trichothecenes present on the surface of spores - can be inhaled deep into the lungs
Made by Stachybotrys - causes sick building syndromes - buildings with structural or mechanical defects - inc. moisture accumulation - trichothecenes present on the surface of spores - can be inhaled deep into the lungs
Fumonisins
Toxin produced by Fusarium sp.
Causes many livestock related problems - Equine Leukoencephalomalacia - holes in brian
Inhibit ceramide synthase - involved in sphingolipid metabolism
Porcine Pulmonary Edema
Esophageal cancer in humans
Causes many livestock related problems - Equine Leukoencephalomalacia - holes in brian
Inhibit ceramide synthase - involved in sphingolipid metabolism
Porcine Pulmonary Edema
Esophageal cancer in humans
GM Corn
Bt toxin genes engineered into it
anti-insect toxin dec. insect damage and dec. fumonisins
anti-insect toxin dec. insect damage and dec. fumonisins
Mycophenolic acid
Produced by P. roqueforti
Immunosuppressive (organ transplants)
Weakly toxic to mice
Immunosuppressive (organ transplants)
Weakly toxic to mice
Patulin
P. roqueforti
Toxic compound associated with apples
Survives pasteurization
Toxic compound associated with apples
Survives pasteurization
Roquefortine C
P. roqueforti toxin
Neurotoxin - causes seizures
Isolated from blue cheeses
Neurotoxin - causes seizures
Isolated from blue cheeses
Citrinin
Penicillium sp.
Nephrotoxin
Turns media yellow
Nephrotoxin
Turns media yellow
Cyclopiazonic acid
Penicillium sp. (and Aspergillus sp.)
Neurotoxin
Neurotoxin
Ochratoxin
Penicillium sp.
Nephrotoxin
Accumulates in animal tissue (pork)
Coffee, wine, chiles
Nephrotoxin
Accumulates in animal tissue (pork)
Coffee, wine, chiles
Tremorgens
Penicillium sp.
Seizures (sheep)
Seizures (sheep)
Cyclopeptides
Attack RNA polymerase in Liver - destroys it
Amatoxins and Phallotoxins
Found in Amanita sp, Galerina autumnalis, Conocybe filaris and Lepiota josserandii
Amatoxins and Phallotoxins
Found in Amanita sp, Galerina autumnalis, Conocybe filaris and Lepiota josserandii
Death Angels
Contain Amatoxins
Produced via special pathway - non-ribosomal protein synthesis
Produced via special pathway - non-ribosomal protein synthesis
Monomethyl hydrazine
Destroys RBCs attacks CNS
Causes N/V diarrhea
Found in false morels - Gyromitra sp.
Causes N/V diarrhea
Found in false morels - Gyromitra sp.
Coprine
Blocks alcohol dehydrogenase - alcohols cannot be completely metabolized
Found in Coprinus atramentarius
Similar to antabuse
Found in Coprinus atramentarius
Similar to antabuse
Muscarine
Induces PSL (perspiration, salivation, lacrimation)
causes cramps, blurred visions, contraction of pupils
Found in Inocybe species, Clitocybe dealbata
causes cramps, blurred visions, contraction of pupils
Found in Inocybe species, Clitocybe dealbata
Ibotenic acid
Old time religion
Found in Amanita muscaria and Amanita pantherina
Expanded perception
Found in Amanita muscaria and Amanita pantherina
Expanded perception
Psilocybin and Psilocin
Found in Psilocybe sp. some Panaeolus sp.
Psychadelic
Trance like state
Psychadelic
Trance like state
About this deck
By: Katie Josephson
Created: 2012-03-25
Size: 23 flashcards
Views: 11
Created: 2012-03-25
Size: 23 flashcards
Views: 11
About StudyBlue
STUDYBLUE makes things that make you better at school.
Things like online flashcards with photos and audio.
Things like personalized quizzes and friendly reminders about when (and what) to study next.
Think of it as a digital backpack™: access to all of your study materials online and on your phone.
STUDYBLUE exists to make studying efficient and effective for every student, for free. Join us.
“I have been getting MUCH better grades on all my tests for school. Flash cards, notes, and quizzes are great on here. Thanks!”
Kathy
Kathy