Psychopharmacology: Chapter 4, pages 105-116
Psychology 436 with Robinson at University of Michigan - Ann Arbor
About this deck
By: James Janisse
Textbook:
Psychopharmacology: Drugs, the Brain and Behavior
Created: 2009-01-19
Size: 19 flashcards
Views: 113
Textbook:
Psychopharmacology: Drugs, the Brain and BehaviorCreated: 2009-01-19
Size: 19 flashcards
Views: 113
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Correlational Relationship
A relationship between two variables where they seemingly have a positive or negative relationship, but a relationship that can never be said to imply causation
Face validity
When an animal test used to evaluate a drug's effects closely resembles the same test used to measure a human's physiological changes. These tests are sometimes for things like blood pressure or body temperature
Construct Validity / Empirical Validity
When an animal test on a drug effect closely parallels or predicts the drug's clinical effect. Tests with high empirical validity can still have low face validity
Reliability
A sign of a good behavioral measurement or other kind of test, when the same results will be recorded each time the test is used
Catalepsy
Being still and immobile, sometimes remaining in an unusual position if positioned that way
Open field test
A non-automated technique of measuring motor activity in animal behavioral experiments, where the animal is in a prescribed area divided into squares which are used by the investigator to record movement
Tail-flick test
A test for an animal's avoidance of a noxious stimulus, to parallel a human's feeling of pain, in which a beam of light directed on a rodent's tail produces heat. The latency of the rodent's reaction is assumed to be correlated with pain intensity
T-maze / multiple T-maze
A maze having a start box at the beginning of an alley with one or more (multiple) choice points that lead to the final goal box, which contains a reward such as a small piece of food. These are used to test spatial learning
Radial arm maze
A special type of maze made up of multiple arms emanating from a central choice point. Used to test spatial memory
Morris water maze
A test for spatial learning where a pool of opaque water contains a small platform hidden just under the surface of the water. The rat is placed in the pool and must find and remember the location of the platform relative to landmarks outside the pool
Light-dark crossing task
A test for animal anxiety in which a two-compartment box has one side brightly lit and the other dark, where measures are made of the amount of time crossing between the two sides and how much time was spent on either
Elevated plus-maze
A test for animal anxiety in which a cross-shaped maze is raised off the floor with two arms enclosed by walls and two walls open. Measurements are made of the time spent in the open or in the enclosed arms
Conditioned emotional response
A test based on learned behaviors where a signal is presented and an electric chock follows to form a classically conditioned association. Has been used to understand the role of the amygdala
Fear-potentiated startle
The enhancement of the startle response to a novel stimulus when that stimulus is preceded by the presentation of a previously conditioned fear stimulus
Conditioned place preference
A method of measuring the rewarding effects of a drug where a drug is conditioned to be associated with a location, and the time spent in that environment over a non-associated one is measured
Schedule of reinforcement
The schedule of rewards in an operant conditioning experiment, which controls the rate and pattern of the animal's behavior and allows us to examine how a drug may affect it
Conflict test
A classic method to evaluate anxiety in animals by creating a conflict between a rewarding action that produces a reinforcer and having that same action be accompanied by an avoidance action such as a foot shocking
Self-administration method
A test of drug reinforcement in rodents that is a very accurate indicator of abuse potential in humans
Breaking point
The point at which the effort required to obtain a drug exceeds the reinforcing value; The higher the breaking point, the more potential for abuse in humans
About this deck
By: James Janisse
Textbook: Psychopharmacology: Drugs, the Brain and Behavior
Created: 2009-01-19
Size: 19 flashcards
Views: 113
Textbook:
Psychopharmacology: Drugs, the Brain and BehaviorCreated: 2009-01-19
Size: 19 flashcards
Views: 113
About StudyBlue
STUDYBLUE makes things that make you better at school.
Things like online flashcards with photos and audio.
Things like personalized quizzes and friendly reminders about when (and what) to study next.
Think of it as a digital backpack™: access to all of your study materials online and on your phone.
STUDYBLUE exists to make studying efficient and effective for every student, for free. Join us.
“I have used this website for three exams, and I see a huge difference in my test results.”
Naj
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