-developed by Walter Sutton
-proposed that genes are present on chromosomes
-based on observations that homologous chromosomes pair with each other during meiosis.
-supportin evidence was provided by work with fruit flies
-controlled by genes present on the x chromosome.
-shows inheritance patterns different than those of genes on autosomes
-uniparental (one parent) inheritance from the mother.
-humans who have gained an extra autosome and they do not survive.
-down syndrome is trisomy of chromosome 21
-humans who have lost even one copy of an autosome
-they generally do not survive embryonic development
-studied Streptococcus pneumoniae, a pathogenic bacterium causing pneumonia
-he infected mice with 2 strains of Streptococcus so he could understand the difference between the 2 strains
-S strain is virulent
-R strain is nonvirulent
-is a nucleic acid
-the building blocks of DNA, each composed of:
-a 5-carbon sugar called deoxyribose
-a phosphate group (PO4)
-a nitrogenous base
adenine, thymine, cytosine, and guanine
-bond between adjacent nucleotides
-formed between the phosphate group of one nucleotide and the 3'--OH of the next nucleotide
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