Chapter 11-Cancer in Children
- Chamberlain College of Nursing
- Pathophysiology Nr281
- Chapter 11-Cancer in Children
Last Modified: 2011-12-09
9500 children up to age 15 are diagnosed annually
1 in every 900 people between the ages of 15-45 will be a survivor of childhood cancer
-having cancer in childhood increases^ yr risk for cancer later in life
originate during uterine life
immature embryonic tissue unable to mature or differentiate into fully developed cells
children with down syndrome have a 10-20 times GREATER risk for developing
osteosarcoma and Ewing's sarcoma(common sites include the femur, pelvis, and humerus)
-aneuploidy, amplifications, deletions, translocations and fragility
-have been associated with the development of childhood&adult cancers
-oncogenes-> mutated genes
nutritional and diet
anabolic androgenic steroids
epstein-barr virus and AIDS
-drugs, second hand smoke, ionizing radiation, viruses
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