What are the 2 Types of Nucleotides and How Do They Pair?
Purine: A & G Pyrimidine: T & C. Pairs must be one of each so that width is consistent with X-ray.
Equal number of A & T bases and G & C bases
What is the Difference Between AT Bonds and GC Bonds
AT: 2 Hydrogen Bonds, GC: 3 Hydrogen Bonds
Sugar-Phosphate Backbone Structure
Phosphate of 1 nucleotide is connected to the sugar of the next, backbone of alternating phosphates & sugars that bases project from. 5' end (has phosphate group) and 3' end (-OH group) refer to #s assigned to carbon in sugar ring. Pgroups - charge
Conservative vs Semiconservative Model
C: Parental strands reassociate after duplication. S: Parental strands separate and serve as templates and new strands contain 1 parent strand and 1 replicated strand
Origins of Replication
2 DNA strands separate opening "bubble" and replication proceeds in both directions from each until molecule copied. Eukaryotic may have hundreds or thousands.