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1) Glomerulus. -C
2) Afferent arteriole. -A
3) Collecting duct. -B
4) Loop of Henle. -E
5) Peritubular capillaries. -D
6) Structure most closely associated with granular cells. -A
7) Medulla of the kidney. -E
A) Site at which most of the tubular reabsorption occurs.
B) Blood supply that directly receives substances from the tubular cells.
C) Site of filtrate formation.
D) Site that drains the distal convoluted tubule.
17) Proximal convoluted tubule.
19) Peritubular capillaries.
20) Collecting duct.
1) If the GFR is too low, needed substances may pass so quickly through the renal tubules that
they are not absorbed and instead are lost in the urine.
2) In the kidneys, the countercurrent mechanism involves the interaction between the flow of
filtrate through the loop of Henle of the juxtamedullary nephrons (the countercurrent multiplier) and the flow of blood through the limbs of adjacent blood vessels (the countercurrent
exchanger). This relationship establishes and maintains an osmotic gradient extending from the cortex through the depths of the medulla that allows the kidneys to vary urine concentration
3) The ureter transports urine from the kidney to the urinary bladder.
4) Water reabsorption through the proximal convoluted tubule is termed obligatory water
reabsorption, whereas water reabsorption through the distal convoluted tubule is termed
facultative water reabsorption.
5) The position of the kidneys behind the
peritoneal lining of the abdominal cavity is described by the term retroperitoneal.
6) The entire responsibility for urine formation lies with the nephron.
8) The act of emptying the bladder is called voiding.True/False
9) Glomerular filtration is an ATP-driven process.True/False
10) In the absence of hormones, the distal tubule and collecting ducts are relatively impermeable
24) The macula densa cells are chemoreceptors that respond to changes in the urea content of the
25) Blood in the urine may be a symptom of bladder cancer.True/False
27) Having a kinked ureter is called renal ptosis.True/FALSE
1) The mechanism that establishes the medullary osmotic gradient depends most on the permeability properties of the ________.
A) loop of Henle
B) glomerular filtration membrane
C) collecting duct
D) distal convoluted tubule
2) Urine passes through the ________.
A) renal hilum to the bladder to the ureter
B) pelvis of the kidney to ureter to bladder to urethra
C) glomerulus to ureter to renal tubule
D) hilum to urethra to bladder
3) Which of the following is not associated with the renal corpuscle?
A) a podocyte
B) a vasa recta
C) a fenestrated capillary
D) an efferent arteriole
4) An increase in the permeability of the cells of the collecting tubule to water is due to a(n) ________.
A) decrease in the production of ADH
B) increase in the production of ADH
C) increase in the production of aldosterone
D) decrease in the concentration of the blood plasma
5) The urinary bladder is composed of ________ epithelium.
B) simple squamous
C) stratified squamous
D) pseudostratified columnar
6) The kidneys are stimulated to produce renin ________.
A) when the peritubular capillaries are dilated
B) when the pH of the urine decreases
C) by a decrease in the blood pressure
D) when the specific gravity of urine rises above 1.10
7) Which of the choices below is not a function of the urinary system?
A) helps maintain homeostasis by controlling the composition, volume, and pressure of blood
B) regulates blood glucose levels and produces hormones
C) maintains blood osmolarity
D) eliminates solid, undigested wastes and excretes carbon dioxide, water, salts, and heat
8) Which gland sits atop each kidney?
9) The ________ artery lies on the boundary between the cortex and medulla of the kidney.
D) cortical radiate
10) The glomerulus differs from other capillaries in the body in that it ________.
A) has a basement membrane
B) is impermeable to most substances
C) is drained by an efferent arteriole
D) has a blood pressure much lower than other organ systems
11) The descending limb of the loop of Henle ________.
A) is not permeable to water
B) is freely permeable to sodium and urea
C) pulls water by osmosis into the lumen of the tubule
D) contains fluid that becomes more concentrated as it moves down into the medulla
12) Select the correct statement about the ureters.
A) Ureters contain sphincters at the entrance to the bladder to prevent the backflow of urine.
B) The epithelium is stratified squamous like the skin, which allows a great deal of stretch.
C) The ureters are capable of peristalsis like that of the gastrointestinal tract.
D) The ureter is innervated by parasympathetic nerve endings only.
13) The fatty tissue surrounding the kidneys is important because it ________.
A) ensures adequate energy for the adrenal glands to operate efficiently
B) stabilizes the position of the kidneys by holding them in their normal position
C) is necessary as a barrier between the adrenal glands and kidneys
D) produces vitamin D
14) The renal corpuscle is made up of ________.
A) Bowman's capsule and glomerulus
B) the descending loop of Henle
C) the renal pyramid
D) the renal papilla
15) The functional and structural unit of the kidneys is the ________.
B) loop of Henle
C) glomerular capsule
D) basement membrane of the capillaries
16) The juxtaglomerular apparatus is responsible for ________.
A) the secretion of drugs
B) the secretion of acids and ammonia
C) reabsorption of organic molecules, vitamins, and water
D) regulating the rate of filtrate formation and controlling systemic blood pressure
17) The chief force pushing water and solutes out of the blood across the filtration membrane is ________.
A) the design and size of the podocytes
B) the thickness of the capillary endothelium
C) glomerular hydrostatic pressure (glomerular blood pressure)
D) the size of the pores in the basement membrane of the capillaries
18) Which of the following statements describes the histology of the ureters?
A) They are trilayered (mucosa, muscularis, and adventitia).
B) They are actually an extension of the visceral peritoneum.
C) They are made up of several layers of endothelium.
D) They are made up entirely of muscle tissue because they need to contract in order to transport urine efficiently.
19) Which of the following statements is a false or incorrect statement?
A) The male urethra serves both the urinary and reproductive systems at the same time.
B) The male urethra serves both the urinary and reproductive systems but at different times.
C) The male urethra is longer than the female urethra.
D) The male urethra is a passageway for both urine and semen.
20) Which of the following acts as the trigger for the initiation of micturition (voiding)?
A) the stretching of the bladder wall
B) motor neurons
C) the pressure of the fluid in the bladder
D) the sympathetic efferents
21) The filtration membrane includes all except ________.
A) glomerular endothelium
C) renal fascia
D) basement membrane
22) The mechanism of water reabsorption by the renal tubules is ________.
A) active transport
C) solvent drag
D) cotransport with sodium ions
23) Most electrolyte reabsorption by the renal tubules is ________.
A) not Tm limited
B) in the distal convoluted tubule
C) hormonally controlled in distal tubule segments
D) completed by the time the loop of Henle is reached
24) The macula densa cells respond to ________.
B) antidiuretic hormone
C) changes in pressure in the tubule
D) changes in solute content of the filtrate
25) Which of the following is not reabsorbed by the proximal convoluted tubule?
26) The fluid in the glomerular (Bowman's) capsule is similar to plasma except that it does not contain a significant amount of ________.
D) plasma protein
27) Alcohol acts as a diuretic because it ________.
A) is not reabsorbed by the tubule cells
B) increases the rate of glomerular filtration
C) increases secretion of ADH
D) inhibits the release of ADH
28) The function of angiotensin II is to ________.
A) constrict arterioles and increase blood pressure
B) decrease the production of aldosterone
C) decrease arterial blood pressure
D) decrease water absorption
29) A disease caused by inadequate secretion of antidiuretic hormone (ADH) by the pituitary gland with symptoms of polyuria is ________.
A) diabetes mellitus
B) diabetes insipidus
C) diabetic acidosis
30) An important characteristic of urine is its specific gravity or density, which is ________.
32) Select the correct statement about the nephrons.
A) The parietal layer of the glomerular capsule is simple squamous epithelium.
B) The glomerulus is correctly described as the proximal end of the proximal convoluted tubule.
C) Podocytes are the branching epithelial cells that line the tubules of the nephron.
D) Filtration slits are the pores that give fenestrated capillaries their name.
34) Which of the following is not a part of the juxtaglomerular apparatus?
A) granular cells
B) macula densa
C) podocyte cells
D) mesangial cells
35) Tubular reabsorption ________.
A) includes substances such as creatinine
B) by active mechanisms usually involves movement against an electrical and/or chemical gradient
C) by passive processes requires ATP to move solutes from the interior of the tubule to the blood
D) is a way for the body to get rid of unwanted waste
36) Which of the following is not a reason why substances are either not reabsorbed or are incompletely reabsorbed from the nephron?
A) They lack carriers.
B) They are not lipid soluble.
C) They are too large to pass through the fenestrations.
D) They are extremely complex molecules.
37) Reabsorption of high levels of glucose and amino acids in the filtrate is accomplished by ________.
A) facilitated diffusion
B) passive transport
D) secondary active transport
38) Which of the choices below is a function of the loop of Henle?
A) form a large volume of very concentrated urine or a small volume of very dilute urine
B) form a large volume of very dilute urine or a small volume of very concentrated urine
C) absorb electrolytes actively with an automatic absorption of water by osmosis
D) none of these
39) Fetal kidneys do not have to work very hard because ________.
A) fetuses do not have any waste to excrete
B) there are no functional nephrons until after birth
C) the placenta allows the mother's urinary system to clear the waste from fetal blood
D) there is no way a fetus could excrete urine until the seventh month of development
40) Which of the following best describes kidney function in older adults (70 years or older)?
A) Kidney function remains the same throughout life, regardless of age.
B) Only about 3% of older adults have any loss of kidney function.
C) Only obese and diabetic older adults have any kidney dysfunction.
D) Kidney function decreases due to kidney atrophy.
41) The factor favoring filtrate formation at the glomerulus is the ________.
A) colloid osmotic pressure of the blood
B) glomerular hydrostatic pressure
C) capsular hydrostatic pressure
D) myogenic mechanism
42) If the Tm for a particular amino acid is 120 mg/100 ml and the concentration of that amino acid in the blood is 230 mg/100 ml, the amino acid will ________.
A) be actively secreted into the filtrate
B) be completely reabsorbed by the tubule cells
C) appear in the urine
D) be reabsorbed by secondary active transport
43) If one says that the clearance value of glucose is zero, what does this mean?
A) The glucose molecule is too large to be filtered out of the blood.
B) Most of the glucose is filtered out of the blood and is not reabsorbed in the convoluted tubules.
C) Normally all the glucose is reabsorbed.
D) The clearance value of glucose is relatively high in a healthy adult.
44) Excretion of dilute urine requires ________.
A) relative permeability of the distal tubule to water
B) impermeability of the collecting tubule to water
C) transport of sodium and chloride ions out of the descending loop of Henle
D) the presence of ADH
45) Which of the choices below is not a method by which the cells of the renal tubules can raise blood pH?
A) by secreting hydrogen ions into the filtrate
B) by reabsorbing filtered bicarbonate ions
C) by producing new bicarbonate ions
D) by secreting sodium ions
46) In the ascending limb of the loop of Henle the ________.
A) thin segment is freely permeable to water
B) thick segment is permeable to water
C) thin segment is not permeable to sodium and chloride
D) thick segment moves ions out into interstitial spaces for reabsorption
47) Select the correct statement about urinary system development.
A) Kidneys develop from urogenital ridges.
B) The metanephric ducts will become the urethras.
C) The pronephros (first tubule system) develops during the tenth week of gestation.
D) The mesonephros will develop into the kidneys.
48) Which of the choices below does not describe the importance of tubular secretion?
A) disposing of substances not already in the filtrate, such as certain drugs
B) eliminating undesirable substances such as urea and uric acid that have been reabsorbed by passive processes
C) ridding the body of bicarbonate ions
D) ridding the body of excessive potassium ions
49) Which statement is correct?
A) Reabsorption of water is hormonally controlled.
B) Normal filtrate contains a large amount of protein.
C) Most of the water passing through the kidney is eliminated as urine.
D) The excretion of sodium ions is one of the mechanisms that maintains the pH balance of the blood.
50) What is the function of the juxtaglomerular apparatus?
A) help regulate blood pressure and the rate of blood filtration by the kidneys
B) help regulate blood pressure and the rate of excretion by the kidneys
C) help regulate urea absorption by the kidneys
D) help regulate water and electrolyte excretion by the kidneys
51) Which of the choices below is the salt level-monitoring part of the nephron?
A) macula densa
B) principal cell
C) vasa recta
D) loop of Henle
52) Which of the hormones below is responsible for facultative water reabsorption?
D) atrial natriuretic peptide
53) Which of the choices below is not a glomerular filtration rate control method?
A) renal autoregulation
B) neural regulation
C) electrolyte levels
D) hormonal regulation
54) Which of the choices below are the most important hormone regulators of electrolyte reabsorption and secretion?
A) angiotensin II and ADH
B) angiotensin II and aldosterone
C) angiotensin I and epinephrine
D) angiotensin I and atrial natriuretic peptide
55) Which cells of the kidney are chemoreceptors that respond to changes in solute content of the filtrate?
A) juxtaglomerular cells
B) mesangial cells
C) macula densa cells
1) The capillary bed that surrounds the descending and ascending loop of Henle of
juxtamedullary nephrons is called the ________.
3) The need to get up in the middle of the night to urinate is called ________.
4) The area between the ureters and urethra is called the ________ in a bladder.
5) The ________ mechanism is the general tendency of vascular smooth muscle to contract when
6) The presence of pus in the urine is a condition called ________.
7) Sodium-linked water flow across a membrane is called ________ water reabsorption.
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