It must be taken into a client's body; be absorbed and distributed to cells, tissues, or a specific organ; and alter physiological functions.
Absorption refers to:
the passage of medication molecules into the blood from the site of medication administration.
Factors that influence medication absorption are:
the route of administration, ability of the medication to dissolve, blood flow to the site of administration, body surface area, and lipid solubility of medication.
Distribution (of medication)
after a medication is absorbed, it is distributed within the body to tissue and organs and ultimately to its specific site of action.
Metabolism (of medication)
After a medication reaches its site of action, it becomes metabolized into a less active form that is easier to excrete.
occurs under the influence of enzymes that detoxify, degrade (break down), and remove biologically active chemicals. Most biotransformation occurs within the liver, although the lungs, kidneys, blood, and intestines also metabolize medications.