Which of the following is primarily responsible for the frequency with which an allele is present in the population?
In using bioinformatics tools to search for possible protein-coding genes in the DNA sequence of the human genome, which of the following would be good evidence for a region being genic?
Presence of a long (100 bp or more) ORF flanked by a “start” and “stop” codon
In a human population, the genotype frequencies at one locus are 0.5 AA, 0.4 Aa, and 0.1 aa. The frequency of the A allele is:
You wish to study the gene product of a eukaryotic gene. For this you want to clone the gene into E. coli (a prokaryote) and use the E.coli to express the gene and produce large amounts of the protein product. The best choice of donor DNA of the eukaryotic gene that you will use to clone into E. coli would be:
a cDNA clone of your eukaryotic gene
You want to amplify a specific DNA sequence from an influenza virus. Which of the following is necessary for the amplification of this DNA by PCR but NOT necessary for amplification by cloning using restriction enzymes?
Knowledge of the sequence of at least some parts of the virus DNA
Which of the following is NOT an assumption of the Hardy-Weinberg law: a) all genotypes have equal viability b)mating is random in the population for the gene in question c)the population is not divided into isolated subpopulations
d)there is variation among individuals within the population
e)the population is infinitely large
there is variation among individuals within the population