Last Modified: 2016-03-08
2. base exision (BER)
3. nucleotide exisision (NER)
ex: A --> G or T --> C
Purine substituted with pyrimidine
* changes codon
* leading cause of chromosome abnormalities
* recruits MutL
2. endonuclease cuts phosphate backbone
3. dna polymerase fills in bases
4 .ligase glues together
2. helicase opens strand
3. polyermase fills in appropriate bases
4. ligase glues together
Horizaontal cut: unchanged
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