Exam 4- HIV/AIDS
- University of Wisconsin - Madison
- Microbiology 101
- Exam 4- HIV/AIDS
Last Modified: 2011-07-02
Related Textbooks:Prescott/Harley/Klein's Microbiology
-intregrases inside of the cell are important for stages in its life cycle
-proteases- important for the assembly of the virus
-has a lipid bilayer
-type 2 is more common in Africa
-NEF (no essential function): essential for damaging macrophages and T4 helper cells...not essential for the growth of the virus
-discovered RNA-dependent DNA polymerase which is the mechanism of infection of retroviruses
-no one knows how to make a vaccine to kill latent cells
2. inhibiting assembly of the virus by inhibiting the protease which blocks the viral assembly
basically sharing blood and bodily fluids
- not much in vaginal/cervical secretions, breast milk, urine, and tears
-none in sweat or feces
-it looks like dTTP but the avido group of AZT cannot serve as a 3'OH for the next nucleotide to attach
-It doesn't inhibit Temin's enzyme but it stops chain growth
-HIV can easily become resistant to AZT
-OraQuick Rapid HIV-1 antibody test takes only 20 minutes and is 99.5% accurate
-genome has 2 identical RNA molecules
-reverse transcriptase, protease, and integrase are all present
-has a second protein shell which is surrounded by a lipid bilayer
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