*AKA Unipolar disorder, SIGECAPS: ≥5 sx in 2 wk periods *Sleep- insomnia, hypersomnia, prob staying asleep *Interest- **depressed mood, irritability (esp kids) *Guilt- worthlessness *Energy- fatigue *Concentration- can't think clearly or make decisions *Appetite- wt change, loss of food enjoyment *Psychomotor- retardation or agitation *Suicide- recurrent thoughts, mostly passive w/out plan
Generalized Anxiety Disorder
*≥3 sx for most days ≥6 mos: WATCHERS Worry Anxiety Tension in muscles Concentration difficulty Hyperarousal (or irritability) Energy loss Restlessness Sleep disturbance (most can't fall asleep)
Mood disorders therapeutic goals
*Sx remission ≥4-5 mos, consider long-term therapy if 2+ episodes *Usually combo of tx: pharm, psycho, social services *Slowly taper off antidepressant therapy, monitor for relapse - incomplete tx w/ partial improvement common w/ >risk for relapse
Electro convulsant therapy
*Consider in severe major dep disorder: function impairment or psychotic sx/catatonia *Urgent response needed - suicidal, refusing food, etc.
Selective serotonin reuptake inhibitors (SSRIs)
*Antidepressants that only act on 5-HT. Most frequently prescribed bc have fewest side effects. *Best effect on lifting and smoothing mood. *Most to least energizing: fluoxetine (Prozac), sertraline (Zoloft), citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil).