What is some general information on felines and some specific requirements?
Most nervous tissue per unit bw, very good reflexes, used widely in neurological research. Complex eye. Sensitivity to neurotoxins. They require lots of space, high fat and protein diet, litter boxes, and perches. Very sociable.
What are the two types of sourcs where cats for laboratory research are acquired?
Class A: facilities which raise speifically cats for research, about 3-4 in the country. Class B: random breeders with no information on health, genetics, or vaccination. High rate of mortality.
What are the various disease models for which cats are useful
Leukemia because of their ability to contract FelV because of similar responses in immune system and pathogenesis of the disease. FIV similar to HIV in progression of disease and pathogenesis. Also heliobacter, which is an agent causing degenerative changes in the gastric mucousa, starting with gastritis and ending with gastric carcinoma. Caused by bacteria, not stress.
Information on cat reproduction…
Onset of cycling can range anywhere from 3.5 to 18 months or with proper nutrition at weight of 2kg. Group housing hastens onset of estrous, and they are seasonally polyestrous starting in Jan-Feb endin in the fall followed by Anestrus. 14 hour photoperiod very important, and can signal estrous within 7-10 weeks. Peak sex occurs 1.5-7yrs, litter size 2-3lits with 3-4kits. Because induced ovulators can mother multiple sires.
What is the result of a cat who reproduced before 1 year of after 8 years of age?
Greater chance of abortion or stillbirth, irregular cycling, birth defects, and smaller litters.
How long after lactation do felines return to normal estrous, and in addition, what is especially odd about the felines ability to reproduce while pregnant?
Following normal lactation, felines will return to estrous approx 4 weeks later. Will sometimes cycle normally during nursing. Should litter abort , feline should become fertile approximately 1 week later. Especially odd, queens can experience estrus DURING pregnancy and ultimately have to undergo parturition of two different aged litters. This is called superfetation.