Functional Development Of The Hematopoietic System
A. Band cell B. Monocyte C. Lymphocyte D. Neutrophil E. Eosinophil F. Basophil G. Red blood cell
What are the two types of Leukocytes?
Granular: 1. Basophils 2. Neutrophils 3. Eosinophils Agranular: 1. Lymphocytes ( T-cell, B-cell, and NK cells) 2. Monocytes
What is the function of the Leukocytes?
•NEUTROPHIL – phagocytosis of bacteria •EOSINOPHIL - defense against parasitic helminths; regulation of inflammatory processes •BASOPHIL – release of histamine and other inflammatory mediators •MONOCYTE – generation of mononuclear-phagocyte system in tissues (macrophages); phagocytosis of protozoa, viruses and senescent cells
What is the function of Platelets?
•COAGULATION – maintain integrity of small blood vessels and stabilize the fibrin plug
What are the functions of Lymphocytes?
•B LYMPHOCYTES – produce immunoglobulins; generate antibody producing plasma cells
•T LYMPHOCYTES – primary mediator of cytotoxicity produce interleukins which control activity of other leukocytes
•NATURAL KILLER CELLS (NK) – lack T and B cell surface markers; kill virally infected and tumor cells without prior stimulation
•All mature blood cells are derived from morphologically unrecognizable hematopoietic progenitor cells which are either: