Find study materials for any course. Check these out:
Browse by school
Make your own
To login with Google, please enable popups
To login with Google, please enable popups
Don’t have an account?
To signup with Google, please enable popups
To signup with Google, please enable popups
Sign up withor
1. A bacteriophage is composed of _______:
a. Protein and fat
b. Carbohydrate and protein
c. Protein and DNA
d. DNA and Carbohydrate
1. In the bacteriophage experiments DNA is labeledwith radioactive ______.
1. In mammalian cells DNA is found in the _____.
d. Endoplasmic reticulum
1. The proteins that assist in DNA packaging inhigher organisms are called _____
1. In DNA base pairing is between ______.
a. A G and C U
b. A T and G U
c. G C and A T
d. C T and G A
1. The two strands of the DNA double helix are heldtogether by ________.
a. Parallel bonds
c. Hydrogen bonds
1. In living cells DNA is normally ______.
a. Loosely packed
b. Tightly and randomly packed
c. Compact and organized
d. All heterochromatin
1. Currently the closest comparable thing to ahuman clone is ______.
a. Fraternal twins
b. Dolly the sheep
c. Identical twins
1. *A bacteriophage placed in media with humantissue culture cells will _______.
a. Kill the cells
b. Replicate independently
c. Do nothingSwim around
1. DNA is composed of a sugar, phosphate and________.
a. A nitrogenous base
b. A carbonic acid
c. 32 Phosphorus
d. hydrogen bonds
1. DNA polymerase removes RNA primers using their______ activity.
d. Error correcting
1. *Some bacterial mRNA 3’ ends can ________.
a. Bind PABPII
b. Look identical eukaryotic 3’ ends
c. Have poly A tails
d. Be terminated by Rho
1. The 5’ end of a eukaryotic mRNA is protected by____.
a. A poly A tail
b. A cap
1. Ori is where _______ begins.
c. DNA replication
d. The promoter
1. Tightly packaged DNA is referred to as _____.
a. Slightly twisted
1. The pyrimidines are ________.
a. G, A
b. G, U
c. G, A, T
d. C, U, T
1. The most ______ packed DNA is found inheterochromatin.
1. *DNA/RNA helicase can _____.
a. Have polymerase activity
b. Separate the DNA strands
c. Remove Okazaki fragmentsd. Terminate transcription
1. The two strands of DNA that make up a doublehelix are oriented 5’ to 3’ and base paired to a strand that is 3’ to 5’. Thisorientation is called ______.
b. The minor groove
1. Phages are ________.
a. Made up of protein and DNA
b. Made up of protein and carbs
c. Made up of protein and lipids
d. Made up of phosphorus and sulfur
1. *DNA replication machinery uses primases to_____.
a. Repair okazaki fragments
b. Make mRNA ends
c. Make tRNA
d. Start replication with complementary RNA.
1. * In the Hershey Chase experiments DNA wasradioactively labeled with __.
a. Phosphorus 32
b. Sulfur 35
c. Carbon 14
d. Nitrogen 15
1. AAUAAA is the signal for ______.
d. Poly A polymerase
1. In Eukaryotes, we can see many different butrelated proteins produced from the same gene due to ________.
c. Gene overlap
d. Promoter interaction
1. * PABPII can be found bound to the _____.
a. 5’ end of eukaryotic mRNA
b. 3’ end of prokaryotic mRNA
c. 3’ end of eukaryotic mRNA
d. 5’ end of eukaryotic or prokaryotic mRNA
1. Each nucleotide is composed of a base,phosphate, and ______.
a. A lipid
b. A sugar
c. Proteind. Sulfur
1. Rolling circle replication starts with a ____ incircular loops of DNA.
1. In eukaryotes, active genes are found in_______.
1. The two primary ways bacterial 3’ endtermination occurs is via ____.
a. Steem loop structures and exonuclease
b. RNA/ DNA helicases and primase
c. mRNA primase and helicase
d. stem loops structures and Rho
1. A direct result of discontinuous DNA synthesisis ___.
a. RNA primers
b. Okazaki fragments
d. DNA pol III
1. The promoter is a specific DNA sequence where_____ begins.
1. The hydrogen bonding seen in DNA and RNA/DNAhybrids is as follows ______.
a. As to Cs, Gs to Cs, and Us to Gs
b. As to Ts, Gs to Cs, and Us to As
c. As to Ts, Ts to Cs, and Us to Gs
d. Gs to Ts, As to Cs, and Us to Gs
1. Each core nucleosome contains two copies each of_______.
a. H3A, H3B, H4, and H5
b. H1, H2, H3, and H4
c. H1, H2A, H2B, and H4
d. H2A, H2B, H3, and H4
1. Splicing results in the removal of ________.
c. Stem loops
d. The 5’ cap
1. T/FThe nucleotides in a strand of DNA are connectedby phosphodiester bonds
a. In DNA guanine forms two hydrogen bonds withcytosine within a strand of DNA.
a. Meselson and Stahl used radioactive helium toinvestigate the nature of DNA replication.
a. A solenoid is made up of nucleosomes.
1. T/FLigase repairs nicks in the DNA strand
a. In a nerve cell, nerve genes will generally befound packaged in euchromatin.
a. The poly A tail found in eukaryotic messages isnot coded for in the gene.
a. DNA is replicated dispersively.
a. DNA replication requires that the two strandsare made at the same rate.
1. *T/FIntrons that have been removed are found in alariat structure.
1. *The initiation of translation begins when the____ binds to the _______.
a. Ribosome small subunit/ ribosome large subunit
b. Ribosome small subunit/ mRNA
c. tRNA/ ribosome large subunit
d. ribosomal small subunit /60S
1. Once a tRNA has entered the ribosome and givenup its amino acid, it leaves from the ______.
a. L site
b. A site
c. E site
d. P site
1. The peptide bond links _____.
b. amino acids
1. An alpha helix found within the structure ofbeta globin would be an example of _______ structure.
1. At the end of translation ______ enters the Asite and binds to the stop codon.
1. On tRNA the three bases that base pair to thethree bases in mRNA are referred to as the _________.
c. Wobble pair
1. * The stop codon codes for the insertion of__________.
a. Glutamic acid
1. The main reason that the genetic code isdegenerate is that the tRNA can ______ in the third position.
a. Error pair
b. Anti-codon pair
c. Wobble pair
d. Primer pair
1. Uncharged tRNA can have a new amino acid addedby _______.
a. DNA polymerase I
c. tRNA synthetase
1. * In bacteria, the ribosome binding site on themRNA is also called the _______ sequence.
1. *In eukaryotes, some proteins are directed tomature in the endoplasmic reticulum by_________.
a. ER factor
b. Release factor
e. The signal recognition particle
1. A mutation that always results in a similarfunctioning protein is called a _____ mutation.
b. Silent mutation
e. Thymine dimer
1. A mutation that results in the suppression ofanother mutation phenotype may be referred to as a _________.
a. Ribosomal suppressor mutatant
b. Missense mutant
c. Wild type
e. Nonsense mutation
1. One characteristic of transposons is the_______.
a. Insertion sequence
b. Introns found in all transposons
c. Size of the transposon
d. Helicase activity
e. Flanking inverted repeats
1. *An example of an intercalating agent is________.
1. Under extreme conditions some normal nucleotidesin DNA can pair incorrectly. This is because they can form ________.
a. Intercalating agents
c. Wobble pairs
d. BromouracilThymine dimers
1. *The RNA world hypothesis holds that RNA was theevolutionary predecessor to the genetic and enzymatic functions of __________
a. DNA and lipids
b. DNA and proteins
c. Proteins and carbs
d. DNA and RNA
e. RNA and polysaccharides
1. A neutral mutation is an acidic-amino acid willresult in a change from one amino acid to ________.
a. A non-polar amino acid
b. An acidic amino acid
c. A stop codon
d. A nonpolar amino acid
e. A basic amino acid
1. *The DNA repair machinery will nick the DNAstrand on either side of an abnormal structure. The site is then repaired by_____.
a. RNA polymerase
c. DNA polymerase I
1. The key enzymatic activity in the ribosome thatfacilitates lengthening of the amino acid chain is ___________.
a. Amino acylation
c. Peptidyl transferase
1. Each tRNAgives up its amino acid in the ribosome and has to be recharged by a__________.
a. tRNA synthetase
d. amino acidase
e. peptidyl transferase
1. *The main cause of sickle cell shaped cells insickle cell anemia is changes in ______structure.
d. Quaternarye. Pentitentiary
1. *TheSanger Method of DNA sequencing used special NTPS to _______ DNA polymerase.
1. In prokaryotes proteins always start with _____.
c. Methyl groups
1. * You inherit your mitochondrial DNA from your________.
d. Mother and father
1. All tRNAs have a modified 3’ that ends with a_____.
1. Translation stops when the stop codon isrecognized by _____.
a. Releasing factor
c. initiation factor
d. transcription factor
e. elongation factor
1. A nonsense mutation is a change _______.
b. From one amino acid to another
c. To a frameshift
d. That is always silent
e. From one amino acid to a stop codon
1. The portion of the tRNA that recognizes the mRNAbases is called the _________.
a. Inverted repeat
c. Amino acid
e. Wobble pair
a. In gel electrophoresis, DNA migrate towards thepositive electrode
a. In corn, the Ac locus can activate thetransposon activity of Ds
a. RFLPs utilize multicloning sites to analyze DNA
a. *Normally, cells cannot repair thymine dimers.
a. A compound that slips in between the bases inDNA and may cause mutation is called an intercalating agent.
a. *Fully functional hemoglobin is an example ofquaternary structure.
a. *The Shine-Dalgarno sequence base pairs withtRNA
a. *Xeroderma pigmentosum is a disorder where DNAreplication is impaired.
a. *Inosine is a modified nucleotide found in tRNA
1. A trait resulting from a mutation in the Ychromosome is called _______.
1. Condensed chromosomes are most easily separatedout for a karyotype during ________.
a. S Phase
1. A person with Turner syndrome is phenotypically_____.
1. The ABO blood system is an example of ________.
a. Partial dominance
b. X linked inheritance
c. Codominanced. Haploidy
1. *The migration of chromosomes to opposingdaughter cells depends on _________.
a. The kinetochore
1. The result of a heterozygous dibhybrid crossratio of _________.
1. In the cell cycle, the S phase is when cells____.
b. Undergo mitosis
c. Replicate DNA
d. Store carbohydrate
1. If one allele is lost due to a deletion yet theother allele produces enough product to maintain the organism, the allele canbe said to be ______.
b. Recessive lethal
1. When crossing horses, parents with two distinctcoat colors can result in progeny with _______coat colors.
1. A gene that results in death of the organism iscalled __________.
b. Lethal allele
1. Variation in coat color in a female cat can bean example of __________.
a. Random X inactivation
c. Partial dominance
d. Turner syndrome
1. *Theappearance of a recessive phenotype in a heterzygote containing the recessivegene on one chromosome and a deletion on the corresponding part of thehomologous chromosome is called _______.
a. Partial dominance
c. Hemizygousd. Barr body
1. An organism that has extra copies of achromosome is referred to as ______.
1. Albinism is a ____ trait.
a. Autosomal dominant
b. Autosomal recessive
c. X-linked dominant
d. X-linked recessive
1. A true breeding stock should be _____ for thedesired trait.
1. With complete recessiveness, the recessiveallele is phenotypically expressed when the organism is ________ for that gene.
c. X linked
1. The cell produced by the fusion of a male andfemale gamete is called a ______.
1. The result of meiosis in female animals is_______.
a. All viable daughter cells
b. 1 viable daughter cell
c. 2 viable daughter cells
d. 3 viable daughter cells
1. *In the case of eye color in drosophiliamelanogaster females heterozygous for the white eye mutation will pass it on totheir sons _______ of the time.
1. *An example of Klinefelter syndrome would be______.
c. Xd. XXY
a. Chromosomes begin to migrate toward opposingpoles during anaphase.
a. *Spermatogenesis produces only one viabledaughter cell.
a. In drosophilia melanogaster, the eye color geneis on the Y chromosome.
a. One consequence of nondisjunction can beaneuploidy.
1. T/FPeople with bloodtype A produce antibodies tobloodtype B.
a. In ABO bloodsystem, A and B are partiallydominant.
a. Recombination can result in chimeric alleles.
a. Males with hemophelia are infertile.
a. Intermediate phenotypes can be seen in partialdominance.
1. T/FTwo parents with achondroplasia will have a 1 in4 chance of having an unaffected child
1. A disease that affects finger length is called______.
1. In a dyhybrid cross where there are two allelesfor each gene and one allele is dominant to the other in each gene the ratio ofthe phenotypes seen is _______.
1. When chromosomes segregate incorrectly we referto this as _______.
b. Sister chromatids
1. When a gene is found on the X chromosome but notthe Y, males can be said to be _____ for that gene.
1. A back cross to a homozygous recessive to testthe genotype of the original individual is called ________.
a. A trihybrid cross
b. Dihybrid cross
c. True breeding
******1. The mosaicism seen in calico cats is caused by_____.
a. An extra Y chromosome
b. Differential x inactivation
c. An abnormal number of x chromosomes
d. An autosomal mutation
1. When a chromosome is described assubmetacentric, the description refers to the position of the ______.
1. The chromosomes that pair during meiosis arereferred to as ___________.
What is the distance in map units between genes k and e?a. 26 map units b. 50 map units
Which of the following statements is true?a. The A and B genes are unlinked.
· Protein produced by mother passed on to progeny whichinitiates coiling of progeny according to her genotype (regardless of herphenotype)
· Mutant of tyrosinase melanin
· Only works at colder temperature
· Seeing if you have the bad allele for BRACAI I
· Sequencing generally won’t be too beneficial for youbecause not much you can do it if have bad allele—doesn’t change treatment
· 2 genes that are really close together there will be avery LITTLE crossing over2 genes that are far away have greater chance ofcrossing over.
· Point mutation (1 nucleotide changed)
· Autosomal recessive blood disorder (RBCS with abnormalridged sickle shapes)
· Autosomal recessive disorder
· Point mutation in chloride channel*
· Viscous secretions* mucous secretions in digestivetract*
· Heterozygotes—relatively prevalent (advantage becausethey are more resistant to bacterial dysentery (people who dye from dehydration(Diarrhea, etc.)
· Adult onset one
· Characterized by CTG repeats (TRIPLET REPEAT)
· Get a nonfunctional protein (this isn’t the problem)
o The problem isthe mRNA filling up the nucleus because there are so many they all cant get out
· Life expenctency about a year
· Trisomy* must worry about having severe abnormalities
· Only tolerate it in a few chromosomes 13, 18, 21
· The one that’s not so bad is SEX (ex:klinefelters—whomay not know they have it until they go try to have kids)
· Primary: basic amino acid
· Secondary: folding and twisting of multiple aminoacids onto themselves (alpha helix, beta pleated sheets)
· Tertiary: 3D folding of multiple secondary structure
· Quaternary: aggregate of fully formed 3D sturcuts,matured protein (can have how ever many number of subunits,
o Very dense andtightly coiled DNA in chrom
o Dark whenstaining
o Seen incentromere and telomere
o Light, looselypacked
o Most transcriptionallyactive part of chrom
o 92% of humangenome
1. During PCR the first step requires that the DNAis single stranded. Making the DNA single stranded is called _________. (dentauring or annealing)
1. A _____ can cause a mutation by inserting itselfinto a gene. (transposon or thymine dimer)
1. Transient abnormal pairing of bases in DNA canlead to mutation if they remain mis-paired during _________. (replication or elongation)
1. UV radiation can lead to formation of ________. (tautomers or thymine dimers)
1. The step where primers hydrogen bond to templateDNA is called _______. (annealing or replication)
1. *There are four vital components in a PCRreaction: template DNA, primers, ________ (dNTPs or ddnTPs), and __________. (Taq DNA polymerase or transposons)
1. The _________ is a transposon found in fruitflies. (p element or agarose)
1. Translation termination ends when UAG binds_________. (post transcriptionally or release factor)
1. *The nucleotides used in sequencing are called________.
1. *Females may produce offspring via ______ in the_______.
1. *Genotypic ally gametes are _______. (diploid or haploid)
1. Males are homozygous for their sex chromosome inthe _____ system.
1. Producing an embryo in the absence offertilization is called ____.
1. The two primary sources of variation in humansfrom generation to generation, is ________, and ___________.
1. When crossing two heterozygous parents where thethere are two alleles. The 3 to 1 ratio is expected to be seen in the ________. (F1 generation or p generation)
1. Intermediate phenotypes in heterozygotes areseen in ______. (partial or codominance)
1. *In humans, recombination occurs during__________. (meiosis or mitosis)
1. Using a homozygous recessive cross to determinethe phenotype of a parent is called a ______.
1. Homologous recombination occurs between sister________.
1. Recombination rates are low around the _______and the _____.
Sign up for free and study better.
Get started today!