Lecture 6 2/4/10 Epidemiology Study of the frequency, distribution, and determinants of an illness in the population Risk factors Basic features of Epidemiological study: Representative samples Onset of disorder determined (age of onset) Accurate diagnoses Incidence ? number of new cases over a certain period of time Prevalence ? number of total cases that exist (old and new) Point ? existing cases at this point in time Period ? existing cases during a period of time (June ?09 ? April ?10) Lifetime ? existing cases over a person?s lifetime Epidemiological Studies of Schizophrenia Risk Factors: Genetic relatedness to a person with Schizophrenia Maleness ? more males than females have Schizophrenia (1.4:1) Higher lifetime risk, higher incidence, but equal prevalence Males more likely to commit suicide (more lethal) Schizophrenia patients have a high risk of suicide Urbanicity More people with Schizophrenia live in cities Hospitals, downward drift (richer move to suburbs), cheaper housing easier to find in cities Migration Lower density of people with a similar background ( higher risk Cultural differences, discrimination, etc. Where you are can affect diagnosis Marijuana use
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