Lecture April 12
- Rutgers University - New Brunswick/Piscataway
- Cell Biology And Neuroscience
- Cell Biology And Neuroscience 356
- Lecture April 12
Last Modified: 2011-05-01
What ion is responsible for repolarization?
difference in concentration of charged particles between different parts of the cell
Membrane only permeable to K+
based on chemical gradient- efflux of K+
generated electrical gradient opposes chemical force- must reach equilibrium potential (no net movement across membrane)
Chemical gradient (much more K+ inside cell)
What energy-costly mechanism is constantly at work to upkeep proper chemical gradients of the cell
electrical potential that would exactly balance chemical potential due to concentration gradient:
E(ion)= (RT/zF) x ln Co/Ci
Purpose of Goldman Equation
What produces hyperpolarization?
negative overshoot due to potassium efflux
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