Development of 1. Male Sex Characteristics 2. Bones and muscle tissue
Inhibition of Protein catabolism Retention of various electrolytes
What is special about Androgens regarding RBCs?
They stimulate the production of RBCs by enhancing production of erythropoietic stimulation factor.
Synthetic Androgens MOA
They stimulate the normal growth and development of the male sex organs and secondary male sex characteristics. They also increase synthesis of body proteins.
How long can the long term dose last?
2 - 3 days to 2 - 4 weeks
What does androgens do in adolescents?
Exogenous androgens accelerate linear growth rates, but may cause disproportionate advancement in bone maturation.
They are a schedule 3 drug.
Adverse Effects of Steroids
Fluid Retention Peliosis of the liver Severe liver effects. Increase in acne, hair loss, irritability, and dizziness. Painful urination Shrinking of Testicles Impotence, sterility, and the development of breasts
What is Peliosis Hepatis?
Uncommon vascular condition characterized by randomly distributed multiple blood filled cavities throughout the liver.
Nursing Implications for Testosterone
IM testosterone should be given deeply
Transdermal Testoderm should be applied to the scrotum