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An immune mediated progressive demyelinating disease of the CNS
multiple sclerosis (MS)
when does MS typically occur?
between the ages of 20-40
common in women
diagnostic findings in an MS patient
-MRI may show plaques
-EEG findings may be abnormal
-lumbar puncture indicates increased gamma globulin
-electrophoresis may indicated an immune system abnormality
Precipitating factors of MS? (onset can occur after these)
causes on MS?
genetic predisposition and viruses
goals of treatment
-delay progression of the disease
-manage chronic symptoms
-prevent and treat acute exacerbations
-dont reccommend hot showers
early symptoms of MS that are typically vague in the beginning
fatigue and weakness
ataxia (uncoordinated movements) and vertigo
tremors and spasticity (lower extremeties)
blurred vision, diplopia, nystagmus (jerking of the eye)
later symptoms of MS?
bowel and bladder disturbances
impaired speech and swallowing
"the great imitator" (you have symptoms related to othere problems)
MS meds that are used (ABC and R drugs)
pt teaching for the ABC and R drugs
-pt needs to learn how to give self injections and alternate sites
-flu like symptoms may occur
what labs do we need to draw for the AB and R drugs?
CBC and liver status
why are corticosteroids given?
-suppress the immune response
-decrease inflammatory changes
-limit the severity nd duration of exacerbations
(weight gain and increased glucose levels may occur)
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