Disorder of carbohydrate metabolism- most commonly occuring carbohydrate metabolism disorder Deficiency of insulin- type 1- juvenile diabetes, complete insulin diabetes. Beta cells dont make insulin Resistance to action of insulin- older age diabetes. Initially is a resistance to beta cells(insulin_) and then a deficency for the body to procduce insulin.
What are the sx of sustained hyperglycemia?
Sustained hyperglycemia, polyuria(sugar is noticed in the urine at 180ml), polydipsia, ketonuria(gives the fruity smell), and weight loss(can't convert the glucose so then start to waste)
type 1 diabetes
Type 1 diabetes- abrupt onset days to weeks) 5% to 10% of all cases Also called insulin-dependent diabetes mellitus (IDDM) Or called juvenile-onset diabetes mellitus Primary defect is destruction of pancreatic beta cells- no longer producing insulin
type 2 Diabetes
Type 2 diabetes Most prevalent form of diabetes Approximately 19 million Americans have it Also called non–insulin-dependent diabetes mellitus (NIDDM) Or called adult-onset diabetes mellitus Obesity is almost always present Insulin resistance and impaired insulin secretion
Short Term Complications of Diabetes.
Short-term Hyperglycemia(can lead to diabetic ketoacidosis- occur from high blood glucose levels- occur in type one) and) hypoglycemia(hypoglycemia coma
Long Term complications of Diabetes- macrovascular.
Long-term Macrovascular(large blood vessels) damage Heart disease(risk equivalant- risk is as high as if you already had an MI) Hypertension- stenotic vessels, Stroke-puts patient at risk for having a stroke. (carotid arteries) Hyperglycemia Altered lipid metabolism- triglycerides are high