- Bloomsburg University of Pennsylvania
- Exercise Science
- Exercise Science 05
- Quiz 2
Last Modified: 2011-05-26
Related Textbooks:Exercise Physiology: Theory and Application to Fitness and Performance
- same rate of flow as systemic circuit
- lower pressure.
- Indicates matching of blood flow to ventilation
- ideal = 1.0
- base is over perfused...<1.0 (bottom) because more blood flow and less air flow
- apex is under perfused >1.0 (top) because there is less blood flow
- Bohr Effect
- Favors "overloading" of O2 to tissues
- During exercise binding of o2 to Hb is less!! this is beneficial because it unloads more oxygen more rapidly to tissues.
- Can reduce fatigue (theoretically) and performance
- Increased blood temperature = a weaker O2-Hb bond
- Rightward Shift of Curve.
- .2-.5*C is enough to shift curve.
- Hypothermic would have a L shift.
- temperature ^ when execising
- RBC must rely on anaerobic glycolysis to meet the cells energy demands.
- a biproduct is 2-3DPG.
- Can combine with hemoglobin and reduce Hb affinity for oxygen
- 2-3 increase with altitude.
- acute immediate response to high altitude
- Myoglobin shuttles o2 from cell membrane to mitochondria
- Bonds more rapidly and at a higher rate then Hb
- Higher affinity for o2
- even at a low pressure (20 mmHG) there is almost 90% saturation
- allows myoglobin (mb) to create o2 stores
- muscles NEEDS o2 supply
- dissolved in plasma (10%)
- Bound to Hb (20%)
- Bicarbonate (70%)
- Contain weak acid groups which accept H ions (COO- and NH3)
- Weak acids capable of accepting H ions
- HCO3- buffers strong acids ---> weak acids
- H2CO3- buffers strong bases ---> weak bases
- Produced during exercise
- Intracellular buffers are the first line of defense
- extracellular buffers are primary means of balancing pH
- Lungs play an important role (reduce LA by removing CO2)
- Metabolic Acidosis
- Respiratory acidosis (hyperventilate)
- Metabolic Alkalosis (vomit)
- Respiratory Alkalosis
- Ve tends to drift upward
- little change in PCO2
- ^ in Ve is not due to ^ PCO2
- receives neural and humoral input
- feedback from muscles
- co2 levels in the blood
- regulates resp. rate
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